منابع مشابه
Big data in biomedicine.
The increasing availability and growth rate of biomedical information, also known as 'big data', provides an opportunity for future personalized medicine programs that will significantly improve patient care. Recent advances in information technology (IT) applied to biomedicine are changing the landscape of privacy and personal information, with patients getting more control of their health inf...
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Philip E. Bourne National Institutes of Health Biomedical research is becoming increasingly data driven, analytical and hence digital. In recognition of this evolution NIH has established the Office for Data Science with trans NIH responsibility for maximizing the value of this digital enterprise. This effort brings together communities, policy changes and new infrastructure to be applied to ex...
متن کاملOpinion: Big data biomedicine offers big higher education opportunities.
I like to tell my students a story about a time back in the “olden days” of the early 1990s when I was a newly minted postdoctoral fellow at the National Institutes of Health (NIH). Our laboratory conducted brain imaging studies using positron emission tomographic imaging and would routinely obtain 6–12 functional image volumes per subject in our experiments. The director of our neuroimaging la...
متن کاملTechnical challenges for big data in biomedicine and health: data sources, infrastructure, and analytics.
OBJECTIVES To review technical and methodological challenges for big data research in biomedicine and health. METHODS We discuss sources of big datasets, survey infrastructures for big data storage and big data processing, and describe the main challenges that arise when analyzing big data. RESULTS The life and biomedical sciences are massively contributing to the big data revolution throug...
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Pleiotropy arises when a locus influences multiple traits. Rich GWAS findings of various traits in the past decade reveal many examples of this phenomenon, suggesting the wide existence of pleiotropic effects. What underlies this phenomenon is the biological connection among seemingly unrelated traits/diseases. Characterizing the molecular mechanisms of pleiotropy not only helps to explain the ...
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ژورنال
عنوان ژورنال: Nature
سال: 2015
ISSN: 0028-0836,1476-4687
DOI: 10.1038/527s1a